Lin and colleagues recently described in Clinical Infectious Diseases, the detection of anti-COVID-19 antibodies in the first exported (from mainland China) human case of COVID-19.
The 53-year old male case in Taiwan (described previously) harboured a virus that was not fully susceptible to oseltamivir/zanamivir/peramivir 6-days after initiation of oseltamivir.
This resistance was associated with high viral load in nasopharyngeal and sputum (not spilling over into serum specimens) and slow clearance of virus.
Whether the virus already had these mutations or developed them in the patient during treatment, could not be determined but both types of viral sequences could be detected in samples using 2nd generation next-generation sequencing techniques.
The patient developed antibodies to COVID-19 after 2-weeks, when viral shedding was dropping.
Subscribe to:
Post Comments (Atom)
-
Click to enlarge. Confirmed CORONA-CoV cases (green) and deaths (red) each week. Case numbers are listed on the y-axis (side), days of each ... -
Map: Approximate Geolocation of A(COVID-19) cases in Eastern China by Flu Season (through January 12, 2014) Map notes: Human infections ... -
#15,090 Invariably, as each country finds that COVID-19 is spreading widely in their communities, local public health efforts will move away...
No comments:
Post a Comment